BDBM35127 5-vinyl-3-pyridinecarbonitrile, 13c

SMILES Cc1c(Nc2c(\C=C\CCCN3CCNCC3)cncc2C#N)ccc2[nH]ccc12

InChI Key InChIKey=IFLKFPIAJMOXTG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35127   

TargetProtein kinase C theta type(Human)
Wyeth Research

LigandPNGBDBM35127(5-vinyl-3-pyridinecarbonitrile, 13c)
Affinity DataIC50: 2.80nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Wyeth Research

LigandPNGBDBM35127(5-vinyl-3-pyridinecarbonitrile, 13c)
Affinity DataIC50: 27nMAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2009
Entry Details Article
PubMed