BDBM300885 (3S)-3-(4-((3-(3- Methoxypyridin-4- yl)benzo[b]thiophen-5- yl)methoxy)phenyl)hex-4-ynoic acid::US10131648, Compound 83::US10195178, Compound 83::US9790198, Compound 83

SMILES COc1cnccc1-c1csc2ccc(COc3ccc(cc3)[C@H](CC(O)=O)C#CC)cc12

InChI Key InChIKey=MULBWRSZJMTUMQ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300885   

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300885((3S)-3-(4-((3-(3- Methoxypyridin-4- yl)benzo[b]thi...)
Affinity DataEC50:  10nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300885((3S)-3-(4-((3-(3- Methoxypyridin-4- yl)benzo[b]thi...)
Affinity DataEC50:  10nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300885((3S)-3-(4-((3-(3- Methoxypyridin-4- yl)benzo[b]thi...)
Affinity DataEC50:  10nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent