BDBM300868 (3S)-3-[4-([3-[2-(2- Methoxyethoxy)-6- methylphenyl]-1- benzothiophen-5- yl]methoxy)phenyl] hex-4-ynoic acid::US10131648, Compound 66::US10195178, Compound 66::US9790198, Compound 66

SMILES COCCOc1cccc(C)c1-c1csc2ccc(COc3ccc(cc3)[C@H](CC(O)=O)C#CC)cc12

InChI Key InChIKey=COCIUAFLKZVBHT-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300868   

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300868((3S)-3-[4-([3-[2-(2- Methoxyethoxy)-6- methylpheny...)
Affinity DataEC50:  14nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300868((3S)-3-[4-([3-[2-(2- Methoxyethoxy)-6- methylpheny...)
Affinity DataEC50:  14nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300868((3S)-3-[4-([3-[2-(2- Methoxyethoxy)-6- methylpheny...)
Affinity DataEC50:  14nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent