BDBM300862 (3S)-3-(4-(((3-(2-Methyl-4-((3- methyl-1,1-dioxidothietan-3- yl)methoxy)phenyl)benzo[b] thiophen-5-yl)oxy)methyl)phenyl) hex-4-ynoic acid::US10131648, Compound 60::US10195178, Compound 60::US9790198, Compound 60

SMILES CC#C[C@@H](CC(O)=O)c1ccc(COc2ccc3scc(-c4ccc(OCC5(C)CS(=O)(=O)C5)cc4C)c3c2)cc1

InChI Key InChIKey=KYBNFPVTJBGAHW-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300862   

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300862((3S)-3-(4-(((3-(2-Methyl-4-((3- methyl-1,1-dioxido...)
Affinity DataEC50:  70nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300862((3S)-3-(4-(((3-(2-Methyl-4-((3- methyl-1,1-dioxido...)
Affinity DataEC50:  70nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300862((3S)-3-(4-(((3-(2-Methyl-4-((3- methyl-1,1-dioxido...)
Affinity DataEC50:  70nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent