BDBM300858 (3S)-3-(4-[[(3-[2-Methyl-4-[(3- methyloxetan-3- yl)methoxy]phenyl]-1- benzothiophen-5- yl)oxy]methyl]phenyl) hex-4-ynoic acid::US10131648, Compound 56::US10195178, Compound 56::US9790198, Compound 56

SMILES CC#C[C@@H](CC(O)=O)c1ccc(COc2ccc3scc(-c4ccc(OCC5(C)COC5)cc4C)c3c2)cc1

InChI Key InChIKey=JCNXJYLYZLAQCJ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300858   

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300858((3S)-3-(4-[[(3-[2-Methyl-4-[(3- methyloxetan-3- yl...)
Affinity DataEC50:  34nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300858((3S)-3-(4-[[(3-[2-Methyl-4-[(3- methyloxetan-3- yl...)
Affinity DataEC50:  34nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300858((3S)-3-(4-[[(3-[2-Methyl-4-[(3- methyloxetan-3- yl...)
Affinity DataEC50:  34nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent