BDBM298368 (S)-1-((S)-1-(4-(benzyloxy)benzoyl)-4,4-difluoropyrrolidine-2-carbonyl)pyrrolidine-2-carbonitrile::US10125097, Example 17::US10611727, Example 17

SMILES FC1(F)C[C@H](N(C1)C(=O)c1ccc(OCc2ccccc2)cc1)C(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=LMPUBXCJEKFGPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298368   

TargetProlyl endopeptidase(Human)
Universitat De Barcelona

US Patent
LigandPNGBDBM298368(US10125097, Example 17 | (S)-1-((S)-1-(4-(benzylox...)
Affinity DataIC50: 287nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
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TargetProlyl endopeptidase-like(Human)
Universitat De Barcelona

US Patent
LigandPNGBDBM298368(US10125097, Example 17 | (S)-1-((S)-1-(4-(benzylox...)
Affinity DataIC50: 287nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent