BDBM298359 (S)-1-((2S,4S)-1-(4-(benzyloxy)-3,5-dimethoxybenzoyl)-4-(trifluoromethyl)-pyrrolidine-2-carbonyl)pyrrolidine-2-carbonitrile::US10125097, Example 8::US10611727, Example 8

SMILES COc1cc(cc(OC)c1OCc1ccccc1)C(=O)N1C[C@H](C[C@H]1C(=O)N1CCC[C@H]1C#N)C(F)(F)F

InChI Key InChIKey=NGNSKOONGZXUQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298359   

TargetProlyl endopeptidase(Human)
Universitat De Barcelona

US Patent
LigandPNGBDBM298359(US10125097, Example 8 | (S)-1-((2S,4S)-1-(4-(benzy...)
Affinity DataIC50: 176nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
Go to US Patent

TargetProlyl endopeptidase-like(Human)
Universitat De Barcelona

US Patent
LigandPNGBDBM298359(US10125097, Example 8 | (S)-1-((2S,4S)-1-(4-(benzy...)
Affinity DataIC50: 176nMAssay Description:POP activity was determined following the method described by Toide et al (Toide K et al., J. Pharmacol. Exp. Ther. 1995; 274:1370-8), using Z-G-P-AM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2020
Entry Details
Go to US Patent