BDBM25422 3-chloro-4-[2-hydroxy-4-(pyridin-2-yl)phenoxy]benzonitrile::Triclosan derivative, 23

SMILES Oc1cc(ccc1Oc1ccc(cc1Cl)C#N)-c1ccccn1

InChI Key InChIKey=CSJXWYZNRAVKKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25422   

TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandPNGBDBM25422(3-chloro-4-[2-hydroxy-4-(pyridin-2-yl)phenoxy]benz...)
Affinity DataIC50: 700nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-acyl-carrier protein reductase(malaria parasite P. falciparum)
International Centre For Science and High Technology

Curated by ChEMBL
LigandPNGBDBM25422(3-chloro-4-[2-hydroxy-4-(pyridin-2-yl)phenoxy]benz...)
Affinity DataIC50: 700nMAssay Description:Inhibition of Plasmodium falciparum enoyl-acyl carrier protein reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed