BDBM2412 1-{2-[alpha-(3-Methylphenyl)phenylmethoxy]ethyl}-2-methyl-5-nitroimidazole::2-methyl-1-{2-[(3-methylphenyl)(phenyl)methoxy]ethyl}-5-nitro-1H-imidazole::Diarylmethoxyethylmethylnitroimidazole (DAMNI) 5

SMILES Cc1ncc(n1CCOC(c1ccccc1)c1cccc(C)c1)[N+]([O-])=O

InChI Key InChIKey=DHGMQDJRQOVYBL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2412   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2412(2-methyl-1-{2-[(3-methylphenyl)(phenyl)methoxy]eth...)
Affinity DataIC50: 300nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2004
Entry Details Article
PubMed