BDBM19880 (2R)-N-(cyanomethyl)-2-[3-(1H-indol-5-yl)phenyl]-4-methylpentanamide::Nonpeptidic Biaryl Nitrile Compound, (R)-42

SMILES CC(C)C[C@@H](C(=O)NCC#N)c1cccc(c1)-c1ccc2[nH]ccc2c1

InChI Key InChIKey=HZRCZFGJFFPTAI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19880   

TargetCathepsin K(Human)
Merck Frosst Centre For Therapeutic Research

LigandPNGBDBM19880((2R)-N-(cyanomethyl)-2-[3-(1H-indol-5-yl)phenyl]-4...)
Affinity DataIC50: 8nMpH: 5.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2008
Entry Details Article
PubMed