BDBM19844 (1R,2S)-N-(cyanomethyl)-2-{2-[4-(methylsulfanyl)phenyl]ethyl}cyclohexane-1-carboxamide::Cyclohexanecarboxamide derivative, 18::racemic mixture

SMILES CSc1ccc(CC[C@@H]2CCCC[C@H]2C(=O)NCC#N)cc1

InChI Key InChIKey=YHPGCHVKCUHXAV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19844   

TargetCathepsin K(Rabbit)
Merck Frosst Centre For Therapeutic Research

LigandPNGBDBM19844(racemic mixture | (1R,2S)-N-(cyanomethyl)-2-{2-[4-...)
Affinity DataIC50: 1.70nMpH: 5.5 T: 2°CAssay Description:Prior to the addition of substrate, different concentrations of the inhibitor ranging from 100 uM to 0.2 nM were preincubated for 15 min with enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2008
Entry Details Article
PubMed