BDBM191652 US9186360, 51::US9186360, 52

SMILES Cn1c2scc(CC(=O)Nc3nc(cs3)-c3ccc(F)c(c3F)C(F)(F)F)c2c(=O)n(C)c1=O

InChI Key InChIKey=XOPMVFNBFICPDB-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 191652   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 52 | US9186360, 51)
Affinity DataIC50: 4.84nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 52 | US9186360, 51)
Affinity DataIC50: 2.49nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 52 | US9186360, 51)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 52 | US9186360, 51)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTransient receptor potential cation channel subfamily V member 3(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 52 | US9186360, 51)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTransient receptor potential cation channel subfamily V member 3(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 52 | US9186360, 51)
Affinity DataIC50: 2.52E+3nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 52 | US9186360, 51)
Affinity DataIC50: 4.57E+3nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 52 | US9186360, 51)
Affinity DataIC50: 3.04E+3nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTransient receptor potential cation channel subfamily M member 8(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 52 | US9186360, 51)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTransient receptor potential cation channel subfamily M member 8(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 52 | US9186360, 51)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 52 | US9186360, 51)
Affinity DataIC50: 6.80nMAssay Description:Antagonist activity at human wildtype TRPA1 channel expressed in CHO-K1 cells tagged with GCaMP6 by measuring calcium flux measured after 24 hrs by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed