BDBM18508 5-[(5-iodo-2-methoxyphenyl)methyl]pyrimidine-2,4-diamine::Diaminopyrimidine, 20

SMILES COc1ccc(I)cc1Cc1cnc(N)nc1N

InChI Key InChIKey=IWLZZQDJSAEWKU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 18508   

TargetDihydrofolate reductase(Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG...)
University of Connecticut At Storrs

LigandPNGBDBM18508(5-[(5-iodo-2-methoxyphenyl)methyl]pyrimidine-2,4-d...)
Affinity DataIC50: 3.73E+4nMpH: 7.0 T: 2°CAssay Description:Enzyme activity assays were performed by monitoring the rate of enzyme-dependent NADPH consumption at an absorbance of 340 nm over a period of severa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2007
Entry Details Article
PubMed