BDBM167932 1,5-Dimethyl-2-phenyl-4-(6-(phenylsulfonyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-1H-pyrazol-3(2H)-one (3)

SMILES Cc1c(-c2c(cnc3ncnn23)S(=O)(=O)c2ccccc2)c(=O)n(-c2ccccc2)n1C

InChI Key InChIKey=FDJUWIFQBPMRKW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 167932   

TargetDipeptidyl peptidase 4 [K6R,T557I](Human)
Cairo University

LigandPNGBDBM167932(1,5-Dimethyl-2-phenyl-4-(6-(phenylsulfonyl)-[1,2,4...)
Affinity DataIC50: 107nMT: 2°CAssay Description:A 200-µL reaction system containing DPP-IV (Sigma), a test compound, and 25 mmol/L HEPES buffer (containing 140 mmol/L NaCl, 1% BSA, and 80 mmol/L Mg...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pcte Group of Institutes

Curated by ChEMBL
LigandPNGBDBM167932(1,5-Dimethyl-2-phenyl-4-(6-(phenylsulfonyl)-[1,2,4...)
Affinity DataIC50: 112nMAssay Description:Inhibition of DPP-4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed