BDBM162249 US9051311, 6

SMILES FC(F)(F)c1ccc(c(c1)C1=CCNCC1)-c1cccc2CN(CCc12)S(=O)(=O)Nc1ncns1

InChI Key InChIKey=RAXMESLBZRICRQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 162249   

LigandPNGBDBM162249(US9051311, 6)
Affinity DataIC50: 22.1nMAssay Description:In Vitro Assays 293 cells stably transfected with either Nav 1.7 or with Nav 1.5 were recorded in population patch-clamp mode with the Ion Works Quat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
Go to US Patent

LigandPNGBDBM162249(US9051311, 6)
Affinity DataIC50: 1.00E+4nMAssay Description:In Vitro Assays 293 cells stably transfected with either Nav 1.7 or with Nav 1.5 were recorded in population patch-clamp mode with the Ion Works Quat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
Go to US Patent

LigandPNGBDBM162249(US9051311, 6)
Affinity DataIC50: 30nMAssay Description:293 cells stably transfected with human Navl .7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
Go to US Patent

LigandPNGBDBM162249(US9051311, 6)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin) expressed in HEK293 cells by IonWorks patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM162249(US9051311, 6)
Affinity DataIC50: 30nMAssay Description:Inhibition of Nav1.7 (unknown origin) expressed in HEK293 cells by PatchXpress methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed