BDBM120275 US8703947, GRL- 1069AL

SMILES COc1cccc(CN2CCN[C@@H]([C@@H](O)[C@H](Cc3ccccc3)NC(=O)c3cccc(c3)C(=O)N3CCC[C@@H]3c3nc(C)cs3)C2=O)c1

InChI Key InChIKey=BVDPRXPLKWPERI-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120275   

TargetBeta-secretase 1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM120275(US8703947, GRL- 1069AL)
Affinity DataKi: <1.00E+3nM ΔG°: <-8.51kcal/molepH: 4.0 T: 2°CAssay Description:The potencies of compounds were determined by measurement of their inhibition of memapsin 2 catalytic activity toward a fluorescent substrate. Kineti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
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