BDBM120268 US8703947, GRL- 0299

SMILES Cc1csc(n1)[C@H]1CCCN1C(=O)c1cccc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)[C@@H]1NCCN(Cc2ccccc2)C1=O

InChI Key InChIKey=VEJXOSJCHPXZKM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120268   

TargetBeta-secretase 1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM120268(US8703947, GRL- 0299)
Affinity DataKi: <1.00E+3nM ΔG°: <-8.51kcal/molepH: 4.0 T: 2°CAssay Description:The potencies of compounds were determined by measurement of their inhibition of memapsin 2 catalytic activity toward a fluorescent substrate. Kineti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
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