BDBM104169 US8575145, 46/47/48/49/50::US8575145, 77::US8575145, 78::US8575145, 79::US8575145, 80

SMILES FC1CCNCCC1Oc1cccc2ccc(nc12)-c1nnc2ccccn12

InChI Key InChIKey=CBZNDVANLGVAAJ-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 104169   

TargetSerine/threonine-protein kinase pim-1(Human)
Array Biopharma

US Patent
LigandPNGBDBM104169(US8575145, 80 | US8575145, 77 | US8575145, 79 | US...)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Array Biopharma

US Patent
LigandPNGBDBM104169(US8575145, 80 | US8575145, 77 | US8575145, 79 | US...)
Affinity DataIC50: 32nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Array Biopharma

US Patent
LigandPNGBDBM104169(US8575145, 80 | US8575145, 77 | US8575145, 79 | US...)
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Array Biopharma

US Patent
LigandPNGBDBM104169(US8575145, 80 | US8575145, 77 | US8575145, 79 | US...)
Affinity DataIC50: 0.920nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Array Biopharma

US Patent
LigandPNGBDBM104169(US8575145, 80 | US8575145, 77 | US8575145, 79 | US...)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM104169(US8575145, 80 | US8575145, 77 | US8575145, 79 | US...)
Affinity DataIC50: 96nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM104169(US8575145, 80 | US8575145, 77 | US8575145, 79 | US...)
Affinity DataIC50: 1.17E+3nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM104169(US8575145, 80 | US8575145, 77 | US8575145, 79 | US...)
Affinity DataIC50: 147nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM104169(US8575145, 80 | US8575145, 77 | US8575145, 79 | US...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Array Biopharma

US Patent
LigandPNGBDBM104169(US8575145, 80 | US8575145, 77 | US8575145, 79 | US...)
Affinity DataIC50: 290nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-3(Rat)
Array Biopharma

US Patent
LigandPNGBDBM104169(US8575145, 80 | US8575145, 77 | US8575145, 79 | US...)
Affinity DataIC50: 41nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-3(Rat)
Array Biopharma

US Patent
LigandPNGBDBM104169(US8575145, 80 | US8575145, 77 | US8575145, 79 | US...)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-3(Rat)
Array Biopharma

US Patent
LigandPNGBDBM104169(US8575145, 80 | US8575145, 77 | US8575145, 79 | US...)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-3(Rat)
Array Biopharma

US Patent
LigandPNGBDBM104169(US8575145, 80 | US8575145, 77 | US8575145, 79 | US...)
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2014
Entry Details
Go to US Patent