BDBM103921 US8569511, 5

SMILES CC1CCN(CC1)c1ccc2nc([nH]c2c1)-c1n[nH]c2ccc(NC(=O)C3CC3(F)F)cc12

InChI Key InChIKey=BRMRDHFLNDECPA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103921   

Target3-phosphoinositide-dependent protein kinase 1(Human)
University of Utah Research Foundation

US Patent
LigandPNGBDBM103921(US8569511, 5)
Affinity DataIC50: 780nMAssay Description:The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2014
Entry Details
Go to US Patent

Target3-phosphoinositide-dependent protein kinase 1(Human)
University of Utah Research Foundation

US Patent
LigandPNGBDBM103921(US8569511, 5)
Affinity DataIC50: 800nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed