BDBM429420 APS-2-16::D3RKN_87::US10548897, Compound 11

SMILES COc1cc2nccc(Nc3ccc(Oc4ccccc4)cc3)c2cc1OC

InChI Key InChIKey=QUTVVSIKCNRGEB-UHFFFAOYSA-N

Data  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 429420   

TargetKinase suppressor of Ras 2(Human)
Icahn School of Medicine At Mount Sinai

US Patent
LigandPNGBDBM429420(APS-2-16 | US10548897, Compound 11 | D3RKN_87)
Affinity DataIC50: 2.50E+3nMAssay Description:The ATP-biotin assay was performed in buffer containing 25 mM Tris pH 7.5, 150 mM NaCl, 10 mM MgCl2, and 2% DMSO. Purified hKSR2-rMEK1 was assayed at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
Go to US Patent

LigandPNGBDBM429420(APS-2-16 | US10548897, Compound 11 | D3RKN_87)
Affinity DataKd:  2.30E+3nMAssay Description:D3R2021More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetTyrosine-protein kinase JAK2(Human)
D3R/Abbott

LigandPNGBDBM429420(APS-2-16 | US10548897, Compound 11 | D3RKN_87)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2022More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

LigandPNGBDBM429420(APS-2-16 | US10548897, Compound 11 | D3RKN_87)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2023More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R