Compile Data Set for Download or QSAR
Report error Found 660 of affinity data for UniProtKB/TrEMBL: P52895
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50427620(CHEMBL2323507 | US9346803, 2)
Affinity DataIC50: 14.5nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50427627(CHEMBL2323474 | US9346803, Table 2, Compound 9: 2-...)
Affinity DataIC50: 35.7nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50427628(CHEMBL2323472 | US9346803, Table 2, Compound 8: 2-...)
Affinity DataIC50: 40.7nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50427622(CHEMBL2323508 | US9346803, Table 2, Compound 10: 3...)
Affinity DataIC50: 49.6nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50427621(CHEMBL2323490 | US9346803, 1)
Affinity DataIC50: 50.1nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50427624(CHEMBL2323522 | US9346803, Table 2, Compound 11: 9...)
Affinity DataIC50: 53.5nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50427629(CHEMBL179587 | US9346803, Table 2, Compound 7: 2-[...)
Affinity DataIC50: 54.5nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50427625(CHEMBL178687 | US9346803, Table 2, Compound 6: 3-[...)
Affinity DataIC50: 57nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50427626(CHEMBL2323481 | US9346803, Table 2, Compound 5: 2-...)
Affinity DataIC50: 81nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50427619(CHEMBL2323511 | US9346803, 3)
Affinity DataIC50: 93nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50293598(2'-des-methyl indomethacin | CHEMBL503179 | US9346...)
Affinity DataIC50: 100nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50623961(CHEMBL194686)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50124577(CHEMBL3623738)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant AKR1C2 (unknown origin) using S-tetralol as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50385711(CHEMBL22815)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50624016(CHEMBL5436838)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50385761(CHEMBL2043313)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50385765(CHEMBL2043318)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50623977(CHEMBL5401700)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50385722(CHEMBL2043310)
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50624003(CHEMBL5398882)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50623963(CHEMBL5426283)
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50623978(CHEMBL5419252)
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50624008(CHEMBL5405863)
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50124575(CHEMBL3623735)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant AKR1C2 (unknown origin) using S-tetralol as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50385766(CHEMBL2043319)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM35901(cid_201986 | flufenamic acid analogue, 28)
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50385762(CHEMBL2043314)
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50623995(CHEMBL5422601)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50385767(CHEMBL2043320)
Affinity DataIC50: 290nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50172470(2-(2-Fluoro-4'-trifluoromethyl-biphenyl-4-yl)-prop...)
Affinity DataIC50: 290nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50623972(CHEMBL5419326)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50623971(CHEMBL5406588)
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50623989(CHEMBL5439918)
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50624000(CHEMBL5414784)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataIC50: 370nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataIC50: 370nMAssay Description:Inhibition of AKR1C2 by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50624010(CHEMBL5396002)
Affinity DataIC50: 370nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50385713(CHEMBL23479)
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50623960(CHEMBL5410510)
Affinity DataIC50: 390nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50385715(CHEMBL2043302)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50623969(CHEMBL5425327)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50623981(CHEMBL5434084)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50385716(CHEMBL2043303)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50337278(2-(phenylamino)benzoic acid | 2-Phenylamino-benzoi...)
Affinity DataIC50: 440nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
Go to US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50337278(2-(phenylamino)benzoic acid | 2-Phenylamino-benzoi...)
Affinity DataIC50: 440nMAssay Description:Inhibition of AKR1C2 by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50337278(2-(phenylamino)benzoic acid | 2-Phenylamino-benzoi...)
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50623976(CHEMBL5439018)
Affinity DataIC50: 440nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50623970(CHEMBL5413682)
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50624009(CHEMBL5423363)
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant AKR1C2 transfected in Escherichia coli BL21 (DE3) pLysS competent cells using S-tetralol as substrate assessed as inh...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
Displayed 1 to 50 (of 660 total ) | Next | Last >>
Jump to: